(US CBP Have relocated the SENTRI Enrollment Office and the I-94 Processing Office)...The offices are in Otay Mesa.
Customs and Border Protection says construction has begun on the existing Otay Mesa Pedestrian Building, doubling the number of pedestrian processing facilities from six to 12 lanes. During the expansion, The SENTRI enrollment office was relocated to the north side of the Commercial Annex Building and the I-94 processing office was relocated to the south side of the same building. The SENTRI office access is by appointment only to pre-approved applicants. The new address is 9725 Via De La Amistad. Information on SENTRI and I-94 processing is available at the CBP website.